Prescott is easily accessible from almost anywhere.

Fly into Phoenix:

Drive North on 17 to to Cordes Junction exit 262 and take 69 North into Prescott.

Drive South from Flagstaff:

Take 17 South to Prescott exit 278 and onto west 169. Follow to end at Route 69. Follow 69 North into Prescott.

Drive from Southern California:

Take 10 east to 60 north to71 north to 89 north into Prescott.

Drive from Northern California:

From California get onto 40 west in Arizona to 89 south into Prescott.